Boston Red Sox ace Chris Sale will miss MLB's Opening Day after being placed on the 15-day injured list.
Sale – a seven-time All-Star and World Series winner – is building up his fitness after suffering from the flu and pneumonia prior to spring training camp with the Red Sox.
The Red Sox will open their season against the Toronto Blue Jays on March 26.
"Nothing at all with the arm," said interim manager Ron Roenicke, who stepped in for Alex Cora after the sign-stealing scandal.
"He's doing really good. We're really happy with where he's at. This is strictly for missing two weeks and then only being able to give him four starts in Spring Training."
Roenicke added: "With the sickness, it cost him two weeks' time and that two weeks is what we'd like to give him to make sure he’s right.
"He's worked hard on getting his arm right. We didn't think four starts in Spring Training was fair to him to make him start the season. He'll open up on the [IL]."
Sale, who hurt his left elbow late last season, made 25 appearances in 2019 – tallying 218 strikeouts and six wins.
The 30-year-old has 2,007 strikeouts in 312 career games since making his debut with the Chicago White Sox in 2010.
"I mean, [my target date] was March 26," said Sale. "Especially given what happened last year and going through this offseason, that was my goal. I wanted to be there. I've let other people do my job and pick up my slack for long enough."
"It was a gut punch," Sale continued. "When we were in that meeting, I said the only thing this hurts is my ego, and that doesn't matter. How can you argue with them just trying to take care of me and do what's best, not only for myself, but for the organisation and the team moving forward?
"They had great points and I didn't. I respect that. Like I said, I respect everybody in that room and the decision was made and you move forward."
|St. Louis Cardinals reliever Jordan Hicks opts out of 2020 season|
|Coronavirus: Dodgers´ Kenley Jansen confirms he had COVID-19|
|Coronavirus: Former NL MVP Posey opts out of 2020 MLB season|
|Coronavirus: MLB announces 83 COVID-19 cases since intake testing|
|Giants catcher Posey misses second straight workout for ´personal issue´|
|MLB endures eventful week of opt outs, positive tests and player concerns|
|MLB includes 9/11 New York tribute in 2021 schedule|
|Coronavirus: Dodgers ace Kershaw to make ninth Opening Day start|
|Coronavirus: Red Sox pitcher Rodriguez tests positive for COVID-19|
|Coronavirus: MLB to open with Yankees v Nationals and Giants v Dodgers on July 23|
|Coronavirus: MLB explains testing delays after complaints|
|Texas Rangers slugger Joey Gallo tests positive for coronavirus|
|Washington Nationals GM Mike Rizzo slams MLB for delayed test results|
|Coronavirus: Nationals reliever Doolittle blasts US over COVID-19 response|
|Cleveland Indians manager favours changing nickname|
|Coronavirus: Braves pitcher Hernandez opts out of 2020 MLB season|
|Coronavirus: Yankees pair LeMahieu and Cessa test positive for COVID-19|
|Coronavirus: Dodgers´ Price opts out of MLB season due to COVID-19 concerns|
|Coronavirus: Giants´ Posey considering opting out of 2020 season|
|Coronavirus: Freddie Freeman among four Braves with COVID-19|
|Cleveland Indians to discuss changing name amid pressure|
|Angels star Trout still unsure if he´ll play in 2020|
|Coronavirus: Blue Jays granted waiver to train in Canada|
|Cubs pitcher Quintana has thumb surgery for laceration|
|Yankees GM ´very optimistic´ Judge will be ready for opening day|
|Rockies OF Desmond opts out of MLB season|
|Nationals duo Zimmerman and Ross join Arizona´s Leake in opting out of MLB season|
|MLB season will be sprint instead of marathon|
|MLBPA agrees to report to camps on July 1, season to start on July 23 or 24|
|Coronavirus: MLB to impose season schedule after union rejects last offer|
|Coronavirus: MLBPA board reportedly rejects 60-game season proposal|
|Coronavirus: Yankees, Mets will both train in New York if MLB season starts|
|MLB tells players it will not agree to more than 60-game season|
|Coronavirus: Astros player tests positive for COVID-19|
|Coronavirus: Five Phillies players test positive|
|Danger of expanded MLB playoffs is rewarding mediocrity|
|Coronavirus: Players counter MLB´s offer with 70-game proposal|
|Coronavirus: MLB Players Trust commits $1million to support minor leaguers|
|MLB, MLBPA nearing agreement for 2020 season?|
|Coronavirus: MLBPA´s Clark says players ´disgusted´ with MLB commissioner Manfred|
|Astros pitcher Justin Verlander throws off mound|
|Coronavirus: MLBPA rejects latest offer, wants MLB to schedule season|
|Coronavirus: Blue Jays hope to play in Toronto, examining other options|
|Detroit Tigers select 1B Torkelson with top pick in MLB Draft|
|Coronavirus: Manfred says there is ´100 per cent´ chance of MLB season|
|GM: Astros would hold ´spring training´ at home park|
|Pirates pitcher Archer out for 2020 season after surgery|
|Coronavirus: David Price gives $1,000 to Dodgers minor leaguers|
|Coronavirus: MLB´s proposal for more salary cuts a non-starter – Scherzer|
|Coronavirus: Tampa Bay Rays open Tropicana Field for limited workouts|
|Rangers would prefer to hold second spring training at new stadium|
|Coronavirus: Nationals to receive World Series rings in virtual ceremony|
|Coronavirus: Former Astros, Athletics manager Howe in ICU with COVID-19|
|With the DH likely coming to all of MLB, which NL hitters would benefit the most?|
|Cashman: Yankees star Judge set to return at full capacity|
|Coronavirus: Rays star pitcher Snell refuses to play unless he gets full salary|
|Coronavirus: Nationals reliever Doolittle concerned about starting MLB season|
|Coronavirus: MLB to bring restart proposal to players, report says|
|Coronavirus: Less than one per cent of MLB employees test positive for COVID-19 antibodies|
|Coronavirus: MLB reportedly shortens 2020 draft from 40 rounds to five|
|Coronavirus: Stars salute return of baseball in South Korea|
|Red Sox outfielder Verdugo says he´s physically 100 per cent|
|Coronavirus: Rays´ Snell wins ´MLB The Show´ Players League championship|
|Former Athletics and All-Star pitcher Keough dies aged 64|
|No fans for MLB games? It´s happened before|
|Astros´ Verlander makes significant progress following groin surgery|
|Coronavirus: Baseball Hall of Fame induction ceremony postponed until 2021|
|Orioles star Mancini not expecting to play in 2020 due to colon cancer|
|Red Sox docked draft pick, Cora suspended one year for sign stealing|
|NTSB: MLB Hall of Famer Roy Halladay had drugs in system, doing stunts when plane crashed|